Extraordinary
Genomics for
Human Health
At Fauna Bio we examine highly conserved genes and pathways when we examine disease resistance across species (using the very high resolution Zoonomia alignments published in Science in April 2023) .
Our platform enriches for human druggable targets in multiple disease areas.
We have curated hundreds of functional genomics studies (RNA seq and proteomics) that we use to examine how genes and pathways function in human disease and preclinical models.
We validate all genes and compound predictions in human cell assays in 2D and 3D in our own wetlab in Emeryville, California with research scientists who are experts at human disease modeling.
We only prioritize targets with strong human genomics support from resources such as the UK Biobank (association studies fully integrated into Convergence (TM)
Our Collaborators
Our Approach
Publications
A comparative genomics multitool for scientific discovery and conservation
Genetic variation drives seasonal onset of hibernation in the 13-lined ground squirrel
Parallel Accelerated Evolution in Distant Hibernators Reveals Candidate Cis Elements and Genetic Circuits Regulating Mammalian Obesity